The Columbia SRP

The Columbia University Northern Plains Partnership for the Superfund Research Program (CUNP-SRP) investigates the health effects, geochemistry, and remediation of arsenic (As) and uranium (U), with a particular focus on groundwater.

Hazardous metals in drinking water, which are common contaminants near Superfund sites and abandoned uranium mines, play a role in the high burden of heart disease and diabetes affecting rural communities in the US Northern Plains, including tribal communities. We have established the CUNP-SRP to generate new knowledge and advance technology to identify mechanisms and solutions to metal exposures using systems science and local knowledge. CUNP-SRP partnership and activities will lay the groundwork for effective interventions to reduce hazardous drinking water contamination affecting communities in the Northern Plains and near abandoned mines and Superfund sites.

Current Research Projects

• Project 1 - High-resolution models of groundwater metal exposure

• Project 2 - Isotopic tracing of sources and cycling of hazardous metal mixtures

• Project 3 - Health Effects of Metals in Native American Communities: A Longitudinal Multi-omics Study

• Project 4 - Causal Molecular Mechanisms Linking Drinking Water Metal Exposures to Cardiometabolic Disease

• Project 5 - Light-based Approaches for Effective and Sustainable Removal of Arsenic and Uranium from Drinking Water Sources

Currently funded by grant P42ES033719 and previously funded by grant P42ES010349 from: