The Exposome Boot Camp: Measuring Exposures on an Omic Scale

 

Exposome Boot Camp TrainingRegistration is open! Join us for the next live-stream Exposome Boot Camp: July 22-23, 2021.

 

The Exposome Boot Camp is a two-day intensive boot camp of seminars and hands-on analytical sessions to provide an overview of concepts, techniques, and data analysis methods used in studies of the exposome.    
  
 

Subscribe for updates on registration and scholarship dates, deadlines, and announcements.


 
 

Boot Camp OVERVIEW

Summer 2021 dates: Live-stream, online training July 22-23, 2021; 10am EDT - ~5pm EDT

There are many challenges to capturing the complexity of exposures in an individual across the lifetime and their potential health effects. Traditionally, environmental health studies have focused on assessing risks related to a single exposure at a time, yet in reality we are constantly exposed to multiple exposures at the same time. To advance environmental health research and positively impact human health through recommendations and policy, we need to incorporate omics data that capture all chemical species detectable in human plasma over the life course. The exposome offers this framework and can be viewed as the environmental complement of the genome.

This two-day intensive boot camp integrates the principle concepts of exposomics and the untargeted approaches of measuring endogenous and exogenous chemical exposures on an omic scale as we step through the tools and techniques currently available to analyze the exposome. Led by a team of expert scientists in the rapidly growing field of exposomics, the boot camp will integrate seminar lectures with hands-on computer lab sessions to put concepts into practice. Emphasis will be given to leveraging existing resources from ongoing studies and initiating new investigations. The afternoon lab sessions will provide an opportunity to work hands-on with real data. Participants will learn and practice data handling, cleaning, and basic analysis of exposomics data.

By the end of the workshop, participants will be familiar with the following topics:

  • Principles of exposomics
  • Concept ideation and study design
  • Laboratory methods and instrumentation platforms for analysis
  • Data extraction and cleaning with emphasis on peaks and feature tables
  • Pathway data analysis and identification databases
  • Data visualization and network interpretation
  • Study design advantages and pitfalls
  • Emerging exposomic topics and laboratory platforms

Investigators at all career stages are welcome to attend, and we particularly encourage trainees and early-stage investigators to participate.

PREREQUISITES AND REQUIREMENTS

This training is designed to accommodate investigators with varying experience levels in R. Knowing R basics is beneficial to maximize training from the boot camp, but is not necessary for you to strongly engage with training material. Data labs will be offered asychronously from the live-stream training and are meant to accommodate both beginner and advanced data manipulation, with all material and additional resources available after the training.  

  1. Each participant must have an introductory background in statistics.

  2. Each participant is required to have a personal laptop. If you would like to participate in the hands-on data labs offered by the Boot Camp, you will need to have R downloaded and installed prior to the first day of the workshop as all lab sessions will be done on your personal laptop. R is available for free download and installation on Mac, PC, and Linux devices.  

  3. The Boot Camp will provide lab tutorials with data sets in R, therefore we recommend participants have a basic understanding of this platform prior to attending the Boot Camp to get the most out of lab sessions, although R knowledge is not required if you do not plan to participate in lab sessions. If you have not used this platform before, step through the tutorials outlined below so you have the basic skills needed for Boot Camp success.

R TUTORIALS

Knowing basic R platform and commands is recommended, but not required, for the Boot Camp as noted in the prerequisites above to get the most out of the lab sessions. If you are new to R or need a refresher, review the below tutorials to be well prepared for the labs: 

If you have any specific questions about R and R studio in the context of the Exposome Boot Camp, please email us.

KEYNOTE SPEAKER

2020: Roel Vermeulen, PhD, Professor, Veterinary Medicine, Department Population Health Sciences, Utrecht University.

INSTRUCTORS

Below is last year's 2020 instructor lineup. The 2021 lineup is still being finalized, but will include similar expertise levels:

Training Director: Gary Miller, PhD, Professor of Environmental Health Sciences and Vice Dean of Research Strategy and Innovation, Mailman School of Public Health, Columbia University. Dr. Miller was the founding Director of the HERCULES Center at Emory University, the first exposome-based research center in the U.S. and authored the first book on the topic, The Exposome: A Primer published by Elsevier. His laboratory at Columbia focuses on environmental drivers of neurodegeneration, using several experimental models from cultured neurons and C. elegans to mice and human studies.

Dean Jones, PhD, Professor of Medicine, Division of Pulmonary, Allergy and Critical Care Medicine, Emory University.

Hector Keun, Professor of Biochemistry, Faculty of Medicine, Department of Surgery and Cancer, Imperial College.

Konstantinos Lazaridis, MD, Gastroenterology and Hepatology Departments, Mayo Clinic.

Megan Niedzwiecki, PhD, Assistant Professor, Department of Environmental Medicine and Public Health, Icahn School of Medicine at Mt. Sinai.

Emma Schymanski, DRN, Associate Professor, FNR ATTRACT Fellow and PI in Environmental Cheminformatics, Luxembourg Centre for Systems Biomedicine (LCSB), University of Luxembourg.

Doug Walker, PhD, Assistant Professor, Department of Environmental Medicine and Public Health, Icahn School of Medicine at Mt. Sinai. Dr. Walker formerly served as the Director of Exposome Research for the Clinical Biomarkers Laboratory and was a member of the HERCULES Exposome Research Center at Emory University. His current research focuses on the continued development and application of advanced analytical strategies for measuring the occurrence, distribution and magnitude of previously unidentified environmental exposures and assist in delineating the mechanisms underlying environment-related diseases in humans.

Krystal Pollitt, PhD, P.Eng., Assistant Professor of Epidemiology (Environmental Health Sciences), Assistant Professor in Chemical and Environmental Engineering, Yale University.

Karan Uppal, PhD, Assistant Professor, Medicine, Emory University.

Jeff Xia, PhD, Assistant Professor, Institute of Parasitology and Department of Agricultural and Environmental Sciences, McGill University.

 

SCHOLARSHIPS

Training scholarships are available for the Exposome Boot Camp.

LOCATION

COVID-19 Update: The Exposome Boot Camp will no longer take place in person due to the COVID-19 pandemic. The Boot Camp will instead be a live-stream, remote training that takes place over live, online video on July 22-23, 2021 from 10am EDT - ~5pm EDT. Please note this training is not a self-paced, pre-recorded online training.

TEStimonials

"The content is new, novel and timely as more fundamental understanding of our environment's role in healthcare outcomes are being investigated." - Academic/Non-Profit Staff member at the Mayo Clinic, 2020

"Very well organized overview of this fascinating and growing field of study.  It was very helpful to enlist national and international experts in Exposomics to reflect the breadth of impact and applicability of this field.  For any researcher studying non-monogenic diseases, this is an essential course for creating a framework that encompasses all non-genetic determinants of disease in a comprehensive fashion." - Setty M., Fellow at the NIH, 2020

"Very enlighten training! It not only showed me the cutting edge of the exposomics field but also provided me with essential hands-on training."Ning S., Staff Member at Exposomics Precision Medicine (Shanghai) Co., 2020

"This was an excellent introduction to the exposome. I entered the bootcamp - run by leaders in the field - a novice and left equipped with an undoubtedly useful working knowledge that will allow me articulate the utility of the exposome to my peers while incorporating the various methodologies into my research program." - Chandra J., Faculty member at the NIH, 2020

"This bootcamp was very inspiring, motivational, and eye-opening. We learnt about the big picture, and also the actual hands-on analysis." - Dandi Q., Faculty member at Harvard Medical School, 2020

"It provided helpful tips and insights for someone who is just dipping their toes in the field of exposomics. I was able to start thinking about my own research in a more purposeful manner, and feel as though I have (virtually) met some experts who would be very happy to answer my questions as I progress through my research." - Student at Rutgers University, 2020

"This boot camp provide me with a comprehensive training on exposome, including instrumental analysis, data processing, and applications in different research areas. What I learned in exposome boot camp will definitely help my on going research." - Postdoc Fellow at the University of Kentucky, 2020

This camp was fantastic and is a must for epidemiologists at all levels of training considering exposome studies." - Christy A., Faculty member at the University of North Carolina, Chapel Hill, 2020

"Nice overview of lab-to-data-analysis pipeline of the -OMICs components of the exposome, and the latest and greatest tools to perform these types of studies." - Postdoc Fellow at the University of Arizona, 2020

The Exposome Boot Camp presents a fascinating introduction to the paradigm shifting field of exposome research, and provides the practical tools and hands-on experience necessary to begin contributing to the field. - Danielle M., Postdoc at Princeton University, 2019

This was an excellent workshop with a combination of experts with both a strong biological and environmental focus, ideal for exposome research, but applicable to other omics style work in general. - Anonymous Faculty member, 2019

The presentations and labs were all fantastic, and I learned so much in a short period of time; it was a really successful way to distill a complex topic. - Briana D., Postdoctoral Fellow at the University of Pittsburgh, 2019

Great experience overall! I found it very seamless and well-organized. A packed 2-day experience with plenty of learning and a great balance of networking and exploring collaborations. - Anonymous Student, 2019

I thought the Boot Camp did a great job of balancing very basic information and detail, providing a very nice "in-depth overview." - Jennifer C., Researcher at IRET, National University in Costa Rica, 2019

I thought this was an amazing bootcamp taught by some truly innovative and forward-thinking scientists. It has a wide-ranging scope and scientists from many branches of science can really benefit from it. - Anonymous Postdoc, 2019

It was a great opportunity to get to learn new ways to implement exposomics. It was also an opportunity to get to know and exchange with new people about our respective work. - Jade C., PhD Student at EHESP - French School of Public Health, 2019

Great overview of this burgeoning field from leading experts in exposome research. Would recommend to anyone who is new to this area of research as a good introduction and opportunity to establish collaborations. - Anonymous Postdoc, 2019

The Exposome Boot Camp is a superb resource for understanding the interconnectedness of our planetary health, linking the totality of lifetime exposures, to the multi-omics, and disease phenotypes. The laboratory sessions provided phenomenal hands-on training on data management, network analysis, and data-driven integration tools. - Ghada S., Associate Professor at the City University of New York, 2019

This boot camp provided an excellent opportunity to learn about many topics related to the exposome from leading scholars in the field. Instructors were incredibly accessible and dedicated to familiarizing the audience with both concepts and and practical tools. - PhD Student, 2019

The Exposome Boot Camp was a really valuable experience.  I learned more about un-targeted mass spec data processing tools available and how they could be used for metabolomics. The Boot Camp offered a unique opportunity to network with people from other fields that are also interested in the exposome. - Kate M., Postdoctoral Fellow at Brown University, 2019

 

REGISTRATION FEES

COVID-19 Update: With the training being offered virtually, we are passing along any and all costs saved to attendees.

  Early-Bird Rate (through 5/15/21) Regular Rate (5/16/21 - 7/15/21) Columbia Discount*
Student/Postdoc/Trainee      $875 $975  10%
Faculty/Academic Staff/Non-Profit Organizations   $975  $1,175 10%
Corporate/For-Profit Organizations $1,175 $1,375 NA

*Columbia Discount: This discount is valid for any active student, postdoc, staff, or faculty at Columbia University. To access Columbia discount, email Columbia.Exposome@gmail.com for instructions and specify if you are paying by credit card, or internal transfer within Columbia.

Invoice Payment and Group Registrations: If you would prefer to pay by invoice/check, or would like to pay for a group of registrants, please email Columbia.Exposome@gmail.com with details.

Registration Fee: This fee includes course material, which will be made available to all participants both during and after the conclusion of the training. 

Cancellations: Cancellation notices must be received via email at least 30 days prior to the training start date in order to receive a full refund, minus a $75 administrative fee. Cancellation notices received via email 14-29 days prior to the training will receive a 75% refund, minus a $75 administrative fee. Please email your cancellation notice to Columbia.Exposome@gmail.comDue to workshop capacity and preparation, we regret that we are unable to refund registration fees for cancellations <14days prior to the training. 

If you are unable to attend the training, we encourage you to send a substitute within the same registration category. Please inform us of the substitute via email at least one week prior to the training to include them on attendee communications, updated registration forms, and materials. Should the substitute fall within a different registration category your credit card will be credited/charged respectively. Please email substitute inquiries to Columbia.Exposome@gmail.com. In the event Columbia must cancel the event, your registration fee will be fully refunded. 

ADDITIONAL INFORMATION

 

 

 

Want updates on new Boot Camp details or registration deadlines? Subscribe here.

Questions? Email the Boot Camp team here.

The Exposome Boot Camp is hosted by Columbia University's SHARP Program in the Mailman School of Public Health and the Irving Institute for Clinical and Translational Research.