Sharon Mannheimer

Sharon Mannheimer

Sharon Mannheimer

Professor of Clinical Medicine
Epidemiology and Medicine at the Columbia University Medical Center


506 Lenox Avenue, Room 3101A
New York NY US 10037
Email: CV:


Sharon Mannheimer, MD is Associate Professor of Clinical Medicine at Columbia College of Physicians and Surgeons, and is also faculty in the Department of Epidemiology in the Mailman School of Public Health. She is based at Harlem Hospital, where she is the Chief of the Division of Infectious Diseases. Dr. Mannheimer's career in Infectious Diseases has focused on HIV, including clinical care of HIV-infected patients, research on adherence to HIV therapy, and also research on HIV prevention. Dr. Mannheimer helps oversee HIV Services at Harlem Hospital including several Ryan White-funded programs, which provide primary care and other supportive HIV services for residents of Harlem and neighboring communities. She also oversees Harlem Hospital's Rapid HIV testing program. In addition, Dr. Mannheimer, as the Assistant Dean of Student Affairs for the Columbia University Medical Center Affiliation at Harlem Hospital, supervises all Columbia medical student activities at Harlem Hospital. She serves on two faculty committees at Columbia's College of Physicians and Surgeons. Dr. Mannheimer is also directly involved in the teaching of Infectious Disease fellows, Medicine residents, and medical students. She is currently involved in conducting HIV prevention research as the Site Leader of the NIH-funded Harlem Prevention Center Clinical Research Site, located in Harlem and part of ICAP in Columbia's Mailman School of Public Health. She is the Site Principal Investigator of the ADAPT Study, an HIV Prevention Trials Network study assessing dosing strategies for pre-exposure prophylaxis (PrEP) medication to prevent HIV infection among at risk HIV negative individuals in New York City. She also serves as the New York City Representative for the Provider Advisory Board of the CDCs Medical Monitoring Project, which assesses HIV care throughout the US. She also previously served as member of the Priority Setting and Resource Allocation Committee of the HIV Health and Human Services Planning Council of New York City, and was a past elected member of the New York State Medical Care Criteria Committee, which develops New York State HIV clinical practice guidelines HIV-infected adults. Dr. Mannheimer's interest in public health stems from her desire to lessen health disparities affecting African Americans related to HIV.



MD, 1989, Case Western Reserve Univ. School of Medicine
BS, 1985, University of Michigan

Mailman Affiliations

Principal Investigator, ICAP

Other Affiliations

Chief, Division of Infectious Diseases, Harlem Hospital Center
Assistant Dean, Student Affairs; Columbia University Affiliation at Harlem Hospital
New York City Representative, Provider Advisory Board, Medical Monitoring Project, Centers for Disease Control
Member, American College of Physicians
Member, Infectious Disease Society of America
Member, International AIDS Society

Areas of Expertise


Select Urban Health Activities

HPTN 067, The ADAPT Study: An NIH-funded HIV Prevention Trials Network (HPTN) Phase II, Randomized, Open-Label, Pharmacokinetic and Behavioral Study of the Use of Intermittent Oral Emtricitabine/Tenofovir Disoproxil Fumarate (truvada) Pre-Exposure Prophylaxis (PrEP) to prevent HIV infection
The STAR Study: Seek, Test, and Retain. Linkages for Black HIV+, Substance Using Men Who Have Sex with Men (STAR) is an NIH/NIDA-funded RO1 study assessing an innovative Respondent Driven Sampling (RDS) method to seek and recruit substance using Black MSM and offer HIV testing to those who agree to enroll. For those who are found to be HIV infected, the study assesses novel interventions to link and retain them in HIV care.

Select Publications

Hodder, S.L., Justman, J., Hughes, J., Wang, J., Haley, D.F., Adimora, A.A., Del Rio, C., Golin, C.Ee, Kuo, I., Rompalo, A., Soto-Torres, L., Mannheimer, S.B., Johnson-Lewis, L., Eshleman, S.H., and El-Sadr, W.M., for the HIV Prevention Trials Network 06 HIV acquisition among women from selected areas of the United States. A cohort study. Ann Intern Med 158 10-18 2013
O'Connor, J.L., Gardner, E.M., Mannheimer, S.B., Lifson, A.R., Esser, S.E., Telzak, E., and Phillips, A.N. for the INSIGHT SMART Study Group. Factors associated with adherence amongst 5,295 people on antiretroviral therapy as part of an international trial. J Infect Dis Epub 2012/12/04. doi: 10.1093/infdis/jis731. PubMed PMID: 23204161 2012
Gardner, E.M., Hullsiek, K.H., Telzak, E.E., Sharma, S., Peng, G., Burman, W.J., MacArthur, R.D., Chesney, M., Friedland, G., and Mannheimer, S.B., for the Terry Beirn Community Programs for Clinical Research on AIDS and the International Network for Stra Antiretroviral medication adherence and class-specific resistance in a large prospective clinical trial. AIDS 24 395-403 2010
Giordano, T.P., Bartsch, G., Zhang, Y., Tedaldi, E., Absalon, J., Mannheimer, S., Thomas, A., and MacArthur, R.D. Disparities in outcomes for African American and Latino subjects in the Flexible Initial Retrovirus Suppressive Therapies (FIRST) trial. AIDS Patient Care STDs 24 287-295 2010
Mannheimer, S., Wold, N., Gardner, E.M., Telzak, E.E., Huppler Hullsiek, K., Chesney, M., Wu, A.W., MacArthur, R.D., Matts, J., and Friedland, G. for the Terry Beirn Community Program for Clinical Research on AIDS (CPCRA). Mild-to-moderate symptoms during the first year of antiretroviral therapy worsen quality of life in HIV-infected individuals. Clin Infect Dis 46 941-945 2008
Gardner, E.M., Sharma, S., Peng, G., Huppler Hullsiek, K., Burman, W.J., MacArthur, R.D., Chesney, M., Telzak, E.E., Friedland, G., Mannheimer, S.B., for the Terry Beirn Community Programs for Clinical Research on AIDS (CPCRA). Differential adherence to combination antiretroviral therapy is associated with virological failure with resistance. AIDS 22 75-82 2008
Mannheimer, S., Thackeray, L., Huppler Hullsiek, K., Chesney, M., Gardner, E.M., Wu, A.W., Telzak, E.E., Lawrence, J., Baxter, J., and Friedland, G. for the Terry Beirn Community Program for Clinical Research on AIDS (CPCRA). A randomized comparison of two instruments for measuring self-reported antiretroviral adherence. AIDS Care 20 161-169 2008
Mannheimer, S.B., Morse, E., Matts, J.P., Andrews, L., Child, C., Schmetter, B. and Friedland, G.H. for the Terry Beirn Community Programs for Clinical Research on AIDS. Sustained benefit from a long-term antiretroviral adherence intervention: Results of a large randomized clinical trial. J Acquir Immune Defic Syndr 43 (suppl 1) S41-S47 2006
Mannheimer, S., Friedland, G., Matts, J., Child, C., and Chesney, M., for the Terry Beirn Community Programs for Clinical Research on AIDS. The consistency of adherence to antiretroviral therapy predicts biologic outcomes for human immunodeficiency virus-infected persons in clinical trials. Clin Infect Dis 34 1115-1121 2002
Telzak, E.E., Sepkowitz, K., Alpert, P., Mannheimer, S., El-Sadr, W., Blum, S., Gagliardi, A., Turett, G. Mulitdrug-resistant tuberculosis among patients without HIV infection. N Engl J Med 333 907-911 1995

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