Yian Gu

Yian Gu

Yian Gu

Assistant Professor of Neurological Sciences
(in Neurology, Epidemiology, the G.H. Sergievsky Center and the Taub Institute)


622 W 168th St., P&H, 18-306
New York NY 10032



Dr. Gu received her training in epidemiology, and her current research aims to understand the role of diet, physical activities, sleep, and other lifestyle factors in brain aging, cognitive aging, and neurodegenerative diseases, and to elucidate the mechanisms for the lifestyle-brain relationship by using multiple biological measures including neuroimaging biomarkers, circulating biomarkers, genetic profiles, etc.



PhD, New York University, New York, NY, USA
MD, Shanghai Medical University, Shanghai, China
MS, Fudan University, Shanghai, China

Mailman Affiliations

Assistant Professor, Department of Epidemiology

Editorial Boards

Current Alzheimer Research

Areas of Expertise

Aging and Elderly, Alzheimer's Disease, Gerontology, Healthy Aging and Longevity, Neurological Disease / Disorders, Environmental Risk Factors, Nutrition

Select Publications

Gu Y, Manly JJ, Mayeux RP, Brickman AM. An inflammation-related nutrient pattern is associated with both brain and cognitive measures in a multiethnic elderly population. Curr Alzheimer Res. 2018 Jan 1. doi:10.2174/1567205015666180101145619. [Epub ahead of print] PubMed PMID: 29298649.

Gu Y, Vorburger R, Scarmeas N, Luchsinger JA, Manly JJ, Schupf N, Mayeux R, Brickman AM. Circulating inflammatory biomarkers in relation to brain structural measurements in a non-demented elderly population. Brain Behav Immun. 2017 Oct;65:150-160. doi: 10.1016/j.bbi.2017.04.022. Epub 2017 Apr 27. PubMed PMID: 28457809; PubMed Central PMCID: PMC5537030.

Gu Y, Vorburger RS, Gazes Y, Habeck CG, Stern Y, Luchsinger JA, Manly JJ, Schupf N, Mayeux R, Brickman AM. White matter integrity as a mediator in the relationship between dietary nutrients and cognition in the elderly. Annals of Neurology; 2016 Jun;79(6):1014-25.

Gu Y, Brickman AM, Stern Y, Habeck CG, Razlighi QR, Luchsinger JA, Manly JJ, Schupf N, Mayeux R, Scarmeas N. Mediterranean diet and brain structure in a multiethnic elderly cohort. Neurology. 2015;85:1744-1751. PMCID: PMC4653103.

Gu Y, Razlighi QR, Zahodne LB, Janicki SC, Ichise M, Manly JJ, Devanand DP, Brickman AM, Schupf N, Mayeux R, Stern Y. The presence of brain amyloid is preceded by accelerated cognitive decline in non-demented older adults: results from a multi-ethnic population. PLoS ONE, 2015 Jul 29;10(7):e0123743. PMCID: PMC4519341.

Gu Y, Shupf N, Cosentino SA, Luchsinger JA, Scarmeas N. Nutrients intake and plasma & β-amyloid. Neurology. 2012 June 5;78 (23):1832-1840. PubMed PMID: 22551728; PubMed Central PMCID: PMC3369517.

Gu Y, Nieves JW, Stern Y, Luchsinger JA, Scarmeas N. Food Combination and Alzheimers disease (AD): a protective diet. Archives of Neurology, 2010;67(6):699-706. Epub 2010 Apr 12. PubMed PMID: 20385883; PubMed Central PMCID: PMC3029147.

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