Shuang Wang, PhD
- Professor of Biostatistics
On the web
Overview
Dr. Shuang Wang's research interest is in the broad area of statistical genetics with an emphasis on genetic linkage and association studies and mapping quantitative trait loci (QTL). Within the two areas, Dr. Wang focuses on the development and application of statistical methods in detecting gene-gene interaction in genetic linkage analysis and linkage disequilibrium analysis using both family-based methods and population-based methods. Dr. Wang is also interested in quantitative trait mapping in out-bred populations, and inferring recombination rates at the population genetics level to identify genomic forces that contribute to this variation. Dr. Wang's other research involves DNA pooling strategy and genetic imprinting effect.
Academic Appointments
- Professor of Biostatistics
Credentials & Experience
Education & Training
- BS, 1998 University of Science and Technology of China
- PhD, 2003 Yale University
Research
Research Interests
- Genetics
Selected Publications
Wang S, Haynes C, Barany F, Ott J Genome-wide autozygosity mapping in Human Populations Genetic Epidemiology In press
Zhao YH, Wang S Optimal DNA Pooling-based Two-Stage Designs in Case-Control Association Studies Human Heredity In press
Hart SN, Wang S, Nakamoto K, Wesselman C, Zhong XB Genetic polymorphisms in cytochrome P450 oxidoreductase influence microsomal P450-catalyzed drug metabolism Pharmacogenet Genom 18 11-24 2008
Zheng L, Wang S, Romans P, Zhao H, Luna C, Benedict M Quantitative trait loci in Anopheles gambiae controlling the encapsulation response against Plasmodium cynomolgi Ceylon BMC Genetics 4 16 2003
Wang S, Zhao HY Sample Size Needed to Detect Gene-Gene Interactions using Linkage Analysis Annals of Human Genetics 71 828-842 2007
Wang S, Huang S, Zheng LB, Zhao HY Mapping Quantitative Trait Loci in Non-inbred Mosquito Crosses Genetics 172 2293-2308 2006
Wang S, Kidd K, Zhao H On the use of DNA pooling to estimate haplotype frequencies Genetic Epidemiology 24 74-82 2003
Wang S, Zhao H Sample size needed to detect gene_gene interaction using association designs American Journal of Epidemiology 158 899-914 2003
Dong C, Wang S, Li W, Li D, Zhao H, Price A Interacting genetic loci on chromosomes 20 and 10 influence extreme human obesity American Journal of Human Genetics 72 115-124 2003
Li W, Li D, Wang S, Zhang S, Zhao H, Price A Linkage and linkage disequilibrium mapping of genes influencing human obesity in chromosome region 7q22.1-C7q35 Diabetes 52 1557-1561 2003