Simon Anthony

Simon Anthony

Simon Anthony

Ecological and evolutionary drivers of virus spillover and disease emergence
Assistant Professor
Epidemiology (in the Center for Infection & Immunity) at Columbia University Medical Center

Office/Address:

722 West 168th Street, 17th Floor
New York NY USA 10033
Phone:
760-500-4639
Website address: Email: Twitter: CV:

Biography

Dr. Anthony's research focuses on the ecology and evolution of viruses - particularly (i) the drivers of trait adaptation by natural selection, co-evolution, and recombination, and (ii) the consequences of this adaptation for spillover risk. It builds on a decade of prior work characterizing viruses of animals, and combines virology with ecology and evolutionary biology to better understand the factors that contribute to the risk of disease emergence in humans and other animals. Currently, his work focuses on RNA viruses, in particular filoviruses (e.g., ebolaviruses) and coronaviruses, and addresses questions such as: (i) What filo-/corona- viruses are circulating in wildlife? Which have the potential for transmission to humans or other animals? And how do eco-evolutionary processes shape key risk factors for disease emergence, such as viral biogeography, pathogenicity traits, and transmission dynamics.

Topics

Education

BSc, 2001, University of Wales, Bangor
PhD, 2007, University of Oxford

Mailman Affiliations

Assistant Professor, Center for Infection and Immunity

Editorial Boards

EcoHealth Journal

Columbia Affiliations

Other Affiliations

Areas of Expertise

Molecular Epidemiology, Global Health, Emerging Infections, Pathogen Discovery, Zoonosis

Select Global Activities

Bangladesh, Brazil, Cambodia, Cameroon, Colombia, Gabon, Indonesia, Laos, Malaysia, Mexico, Nepal, Peru, Rwanda, Tanzania, Thailand, Uganda, Vietnam
World

Select Publications

Goldstein, T*; Anthony, SJ*; Gbakima, A; Bird, BH; Bangura, J; Tremeau-Bravard, A; Belaganahalli, M; Wells, H; Dhanota, JK; Liang, E; Grodus, M; Jangra, R; DeJesus, V; Lasso G; Smith, B; Jambai, A; Kamara, BO; Kamara, S; Bangura, W; Monagin, C; Shapira, S; Johnson, C.K; Saylors, K; Rubin, E; Chandran, K; Lipkin, WI; Mazet, JAK. The discovery of Bombali virus adds further support for bats as hosts of ebolaviruses. 2018. Nature Microbiology. 3, pages 1084–1089 *Authors contributed equally
Anthony, S.J; Johnson, C.K; Greig, D.J; Kramer, S; Che, X; Wells, H; Hicks, A.L; Joly, D.O; Wolfe, N.D; Daszak, P; Karesh, W; Lipkin, W.I; Morse, S.S; PREDICT Consortium; Mazet, J.A.K; Goldstein, T. Global patterns in coronavirus diversity. 2017. Virus Evolution. 12;3(1):vex012. doi: 10.1093/ve/vex012
Anthony, S.J; Gilardi, K; Goldstein, T; Ssebide, B; Mbabazi, R; Navarrete-Macias, I; Liang, E; Wells, H; Hicks, A; Petrosov, A; Byarugaba, D.K; Debbink, K; Yount, B.L; Menachery, V.D; Cranfield, M; Johnson, C.K; Baric, R.S; Lipkin, W.I; Mazet, J.A.K. Further evidence for bats as the evolutionary source of MERS Coronavirus. 2017. mBio vol. 8 no. 2 e00373-17. doi: 10.1128/mBio.00373-17
Epstein, J.E; Anthony, S.J; Islam, A; Kilpatrick, A.M; Ali Khan, S; Ross, N; Smith, I; Barr, J; Zambrana-Torrelio, C; Tao, Y; Quan, P.L; Olival, K; Gurley, E; Hossain, M.J; Field, H.E; Fielder, M; Briese, T; Rahman, M; Crameri, G; Wang, LF; Luby, S; Lipkin, WI; Daszak, P. Nipah virus ecology and infection dynamics in its bat reservoir, Pteropus medius, in Bangladesh 2016. International Journal of Infectious Diseases. 53: 20-21
Anthony, S.J; St. Leger, J.A; Liang, E; Hicks, A.L; Sanchez-Leon, M.D; Jain, K; Lefkowitch, J; Navarrete-Macias, I; Knowles, N; Solovyov, A; Goldstein, T; Pugliares, K; Ip, H.S; Rowles, T; Lipkin, W.I. Discovery of a novel hepatovirus (Phopivirus of seals) related to human hepatitis A virus. 2015. mBio 6(4):e01180-15. doi:10.1128/mBio.0118 0-15
Anthony, S.J; Islam, A; Johnson, C; Navarrete-Macias, I; Liang, E; Jain, K; Hitchens, P.L; Che, X; Soloyvov, A; Hicks, A.L; Ojeda-Flores, R; Ulrich, W; Rostal, M.K, Epstein, J.H; Petrosov, A; Garcia, J; Haider, N; Wolfe, N; Goldstein, T; Morse, S.S; Rahman, M; Mazet, J; Daszak, P; Lipkin, W.I. Non-random patterns in viral diversity. 2015. Nature Communications 6: 8147. doi:10.1038/ncomms9147
Anthony, S.J; Epstein, J.H; Murray, K.A; Navarrete-Macias, I; Zambrana-Torrelio, C.M; Solovyov, A; Ojeda-Flores, R; Arrigo, N.C; Islam, A; Ali Khan, S; Hosseini, P; Bogich, T.L; Olival, K.J; Sanchez-Leon, M.D; Karesh, W; Goldstein, T; Luby, S.P; Morse, S.S; Mazet, JAK; Daszak, P; Lipkin, W.I. A strategy to estimate unknown viral diversity mammals. 2013. mBio 4(5): e00598-13
Olival, K.J; Islam, A; Yu, M; Anthony, S.J; Epstein, J.H; Khan, S.A; Khan, S.U; Crameri, G; Wang, LF; Lipkin, W.I; Luby, S.P; Daszak, P. Filovirus Infection in Fruit Bats (Rousettus leschenaultii), Bangladesh 2013. Emerging Infectious Diseases. doi: 10.3201/eid1902.120524
Anthony, S.J; St Leger, J.A; Pugliares, K; Ip, H.S; Chan, J.M; Carpenter, Z.W; Navarette-Macias, I; Sanchez-Leon, M; Saliki, J.T; Pedersen, J; Karesh, W; Daszak, P; Rabadan, R; Rowles, T; Lipkin, W.I. Emergence of fatal influenza in New England Harbor seals. 2012. mBio 3(4):e00166-12. doi:10.1128/mBio.00166-12
Anthony, SJ; Darpel, K.E; Belaganahalli, M.N; Maan, N; Nomikou, K; Sutton, G; Attoui, H; Maan, S; Mertens, P.P.C. RNA segment 9 exists as a duplex concatemer in an Australian strain of epizootic haemorrhagic disease virus (EHDV): Genetic analysis and evidence for the presence of concatemers as a normal feature of orbivirus replication. 2011. Virology 420: 164-171

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