Xiaoyu (Jason) Che

Assistant Professor of Biostatistics
Phone: 212.342.5176
Fax: 212.342.9044
Email: xc2273@cumc.columbia.edu


Zhejiang University, BS (2006)
Claremont Graduate University, PhD (2013)


Survival Analysis
Counting Processes
Semiparametric Models
Data Mining & Machine Learning
Statistical applications in systems biology for chronic and emerging infectious diseases


Williams SH, Che X, Oleynik A, Garcia J, Muller D, Zabka TS, Firth C, Corrigan RM, Briese T, Lipkin WI. Discovery of two highly divergent negative sense RNA viruses associated with the parasitic nematode, Capillaria hepatica, in wild Mus musculus from New York City. J Gen Virol. 2019 Oct;100(10):1350-1362. doi: 10.1099/jgv.0.001315

Shije J, Ukaigwe J, Che X, Brannagan T, Hornig M. Serum Cytokines and Chemokines in Chronic Inflammatory Demyelinating Polyneuropathy Compared to Diabetic Neuropathy, Idiopathic Neuropathy and Other Inflammatory Neuropathies. Neurology. 2019 Apr;92(15 Supplement):P2.4-002. Link

Nagy-Szakal D, Barupal DK, Lee B, Che X, Williams BL, Kahn EJR, Ukaigwe JE, Bateman L, Klimas NG, Komaroff AL, Levine S, Montoya JG, Peterson DL, Levin B, Hornig M, Fiehn O, Lipkin WI. Insights into myalgic encephalomyelitis/chronic fatigue syndrome phenotypes through comprehensive metabolomics. Sci Rep. 2018 Jul;8(1):10056. doi: 10.1038/s41598-018-28477-9

Williams SH, Che X, Paulick A, Guo C, Lee B, Muller D, Uhlemann AC, Lowy FD, Corrigan RM, Lipkin WI. New York City house mice (Mus musculus) as potential reservoirs for pathogenic bacteria and antimicrobial resistance determinants. mBio. 2018 Apr;9(2). doi: 10.1128/mBio.00624-18

Williams SH, Che X, Garcia J, Klena JD, Lee B, Muller D, Ulrich W, Corrigan R, Nichol S, Jain K, Lipkin WI. Viral diversity of house mice in New York City. mBio. 2018 Apr;9(2). doi: 10.1128/mBio.01354-17

Mishra N, Caciula A, Price A, Thakkar R, Ng J, Chauhan LV, Jain K, Che X, Espinosa DA, Montoya Cruz M, Balmaseda A, Sullivan EH, Patel JJ, Jarman RG, Rakeman JL, Egan CT, Reusken CBEM, Koopmans MPG, Harris E, Tokarz R, Briese T, Lipkin WI. Diagnosis of Zika Virus Infection by Peptide Array and Enzyme-Linked Immunosorbent Assay. mBio. 2018 Mar;9(2). doi: 10.1128/mBio.00095-18

Hornig M, Bresnahan MA, Che X, schultz AF, Ukaigwe JE, Eddy ML, Hirtz D, Gunnes N, Lie KK, Magnus P, Mjaaland S, Reichborn-Kjennerud T, Schjølberg S, Øyen AS, Levein B, Susser ES, Stoltenberg C, Lipkin WI. Prenatal fever and autism risk. Mol Psychiatry. 2018 Mar;23(3):759-766. doi: 10.1038/mp.2017.119

Anthony S, Johnson CK, Greig DJ, Kramer S, Che X, Wells H, Hicks A, Joly D, Wolfe N, Daszak P, Karesh W, Lipkin WI, Morse SS, PREDICT Consortium, Mazet JAK, Goldstein T. Global patterns in coronavirus diversity. Virus Evol, 2017 Jun;3(1):ves012. doi: 10.1093/ve/ves012

Mahic M, Che X, Susser ES, Levin B, Reichborn-Kjennerud T, Magnus P, Stoltenberg C, Chauhan L, Briese T. Bresnahan MA, Surén P, Hornig M, Mjaaland S, Lipkin WI. Epidemiological and Serological Investigation into the Role of Gestational Maternal Influenza Virus Infection and Autism Spectrum Disorders. mSphere. 2017 May;2(3). doi: 10.1128/mSphere.00159-17

Nagy-Szakal D, Williams BL, Mishra N, Che X, Lee B, Bateman L, Klimas NG, Komaroff AL, Levine S, Montoya JG, Peterson DL, Ramanan D, Jain K, Eddy ML, Hornig M, Lipkin WI. Fecal metagenomic profiles in subgroups of patients with myalgic encephalomyelitis/chronic fatigue syndrome. Microbiome. 2017 Apr;5(1):44. doi: 10.1186/s40168-017-0261-y

Che X, Angus J. A new joint model of recurrent event data with the additive hazards model for the terminal event time. Metrika (Springer). 2016 Oct;79(7):763-787. doi: 10.1007/s00184-016-0577-9
Anthony SJ, Islam A, Johnson C, Navarrete-Macias I, Liang E, Jain K, Hitchens PL, Che X, Soloyvov A, Hicks AL, Ojeda-Flores R, Zambrana-Torrelio C, Ulrich W, Rostal MK, Petrosov A, Garcia J, Haider N, Wolfe N, Goldstein T, Morse SS, Rahman M, Epstein JH, Mazet JK, Daszak P, Lipkin WI. Non-random patterns in viral diversity. Nat Commun. 2015 Sep;6:8147. doi: 10.1038/ncomms9147

Hornig M, Gottschalk G, Peterson DL, Knox KK, Schultz AF, Eddy ML, Che X, Lipkin WI. Cytokine network analysis of cerebrospinal fluid in myalgic encephalomyelitis/chronic fatigue syndrome. Mol Psychiatry. 2015 Feb;21(2):261-269. doi: 10.1038/mp.2015.29

Hornig M, Montoya JG, Klimas NG, Levine S, Felsenstein D, Bateman L, Peterson DL, Gottschalk CG, Schultz AF, Che X, Eddy ML, Komaroff AL, Lipkin WI. Distinct plasma immune signatures in ME/CFS are present early in the course of illness. Sci Adv. 2015 Feb;1(1). doi: 10.1126/sciadv.1400121

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