Iuliana Ionita-Laza, PhD

  • Professor of Biostatistics
Profile Headshot


My main research interests lie at the interface between statistics and genomics. I am particularly interested in developing statistical and machine learning methods for the analysis of high-dimensional genetic and functional genomics data. I am also involved in applications of such methods to understand the genetic basis of complex diseases and traits, including autism spectrum disorders, schizophrenia and Alzheimer's disease.

Academic Appointments

  • Professor of Biostatistics

Credentials & Experience

Education & Training

  • PhD, 2006 Courant Institute of Mathematical Sciences, NYU

Editorial Boards

Associate Editor, Biometrics

Associate Editor, Statistics in Biosciences

Honors & Awards

Janet Fabri Prize, Courant Institute of Mathematical Sciences, 2007

Dean's Dissertation Fellowship, New York University, 2005-2006


Research Interests

  • Chronic disease
  • Genetics
  • Global Health

Selected Publications

I Ionita-Laza, NM Laird On the optimal design of genetic variant discovery studies Statistical Applications in Genetics and Molecular Biology 2010

I Ionita-Laza, J Buxbaum, N Laird and C Lange A new testing strategy to identify rare variants with either risk or protective effect on disease PloS Genetics 2011

Iuliana Ionita-Laza, Christoph Lange, Nan Laird On a method to count the number of unseen variants in the human genome Proc Natl Acad Sci 106 5008-5013 2009

David Fardo, Iuliana Ionita-Laza, Christoph Lange On quality control measures in genome-wide association studies: A test to assess the genotyping quality of individual probands in family-based association studies and an application to the HapMap data Plos Genetics 2009

Lars Bertram, Christoph Lange et al., Iuliana Ionita-Laza, et al. R Tanzi Genome-wide Association Analysis Reveals Putative Alzheimer's Disease Susceptibility Loci in Addition to APOE American Journal of Human Genetics 83 623-632 2008

Jinbo Fan*, Iuliana Ionita-Laza*, et al., Nan Laird, Jordan Smoller Linkage Disequilibrium Mapping of the Chromosome 6q21-22.31 Bipolar I Disorder Susceptibility Locus Neuropsychiatric Genetics 2009

Iuliana Ionita-Laza, Nan Laird, Benjamin Raby, Scott Weiss, Christoph Lange On the frequency of copy number variants Bioinformatics 24 2350-2355 2008

Iuliana Ionita-Laza, Angela Rogers, Christoph Lange, Benjamin Raby, Charles Lee Genetic association analysis of copy number variation in human disease pathogenesis Genomics 93 22-26 2009

Iuliana Ionita-Laza, George Perry, Benjamin Raby, Barbara Klanderman, Charles Lee, Nan Laird, Scott Weiss, Christoph Lange On the analysis of copy-number variations in genome-wide association studies: A translation of the family-based association test Genetic Epidemiology 32 273-284 2008

Iuliana Ionita-Laza, Matthew McQueen, Nan Laird, Christoph Lange Genomewide Weighted Hypothesis Testing in Family-Based Association Studies, with an Application to a 100K Scan American Journal of Human Genetics 81 607-614 2007

Iuliana Ionita, Raul-Sam Daruwala, Bud Mishra Mapping Tumor Suppressor Genes using Multipoint Statistics from Copy-Number Variation Data American Journal of Human Genetics 79 13-22 2006

Iuliana Ionita, Shaw-Hwa Lo Multilocus Linkage Analysis of Affected Sib Pairs Human Heredity 60 227-240 2005