Dean Jones

  • Adjunct Professor of Environmental Health Sciences
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Dean P. Jones, PhD is Professor of Medicine (Division of Pulmonary, Allergy, Critical Care and Sleep Medicine) and Biochemistry at Emory University, Atlanta, GA.  He is the Director of the Clinical Biomarkers Laboratory, Director of the Integrative Health Sciences Facility Core of the NIEHS-supported HERCULES Environmental Health Center and Co-Director of the Center for Clinical and Molecular Nutrition.  He received a BS (1971) with honors in Chemistry and Biochemistry from the University of Illinois, Urbana.  He trained with Howard S Mason, PhD, a pioneer in xenobiotic metabolism, at the Oregon Health Sciences University for his PhD (1976).  He was a National Sciences Foundation Postdoctoral Fellow in Nutritional Biochemistry at Cornell University, Ithaca, and a Visiting Scholar in Molecular Toxicology at the Karolinska Institute, Stockholm, studying toxicologic mechanisms of cell death with the leading authority, Sten Orrenius, MD, PhD.  He joined the faculty of Emory University in Biochemistry in 1979, promoted through the ranks and moved to the Department of Medicine to found the Clinical Biomarkers Laboratory in 2003.  In 1997, he was appointed Nobel Fellow at the Karolinska Institute, Stockholm.  He has served in several leadership roles at Emory University, including Program Director of Nutrition Health Sciences, Radiation Safety Officer, Laboratory Director of the General Clinical Research Center, and Executive Committee of the Emory-Georgia Tech Predictive Health Institute.

Dr. Jones studies redox biology and medicine, and currently has research programs in oxidative stress, redox systems biology and exposome medicine, with extensive collaborations in environmental epidemiology and health. Dr. Jones is recognized for his research in oxidative mechanisms of disease, subcellular redox compartmentalization and high-resolution metabolomics and exposomics.  He has developed many methods for analytical biochemistry and received many patents; his method for human plasma glutathione measurement is the most widely used method and the metabolomics methods developed by his team have been used to support hundreds of investigators in population, clinical and translational research.  Dr. Jones has over 600 peer-reviewed publications with over 65,000 literature citations. He has received numerous research, mentorship and leadership awards.  His research has been supported by the National Institute of Health Sciences (NIH Office of the Director, NIEHS, NHLBI, NIA, NIDDK, NIAAA, NCI, NEI, NIAID), Department of Defense, Office of Naval Research, American Heart Association and American Institute for Cancer Research.  He has served on multiple editorial boards and grant review panels, including regular membership on NIH Alcohol and Toxicology (Chair), NCI Basic Mechanisms of Cancer Therapeutics, NIH Systemic Injury by Environmental Exposure and ad hoc participation in more than 40 others.

Academic Appointments

  • Adjunct Professor of Environmental Health Sciences

Credentials & Experience

Education & Training

  • BS, 1971 University of Illinois
  • PhD, 1976 Oregon Health Sciences University


Selected Publications

Liu, K.H., Lee, C.M., Singer, G., Bais, P., Castellanos, F., Woodworth, M.H., Ziegler, T.R., Kraft, C.S., Miller, G.W., Li, S., Go, Y.M., Morgan, E.T., Jones, D.P. (2021). Large scale enzyme based xenobiotic identification for exposomics. Nat Commun, 12(1):5418.

Hu, X., Walker, D.I., Liang, Y., Smith, M.R., Orr, M.L., Juran, B.D., Ma, C., Uppal, K., Koval, M., Martin, G.S., Neujahr, D.C., Marsit, C.J., Go, Y.M., Pennell, K.D., Miller, G.W., Lazaridis, K.N., Jones, D.P. (2021). A scalable workflow to characterize the human exposome. Nat Commun,12(1):5575. PMCID: PMC8458492

Y.-M. Go, M.R, Smith, D.I. Walker, K. Uppal, P. Rohrbeck, P.L. Krahl, P.K. Hopke, M.J. Utell, T.M. Mallon, D.P. Jones.  Metabolome-wide Association Study of Deployment to Balad, Iraq or Bagram, Afghanistan. (2019). J Occup Environ Med. 61(Suppl 12): S25-S34.  PMCID: PMC6901093

Liu, K.H., Nellis, M., Uppal, K., Ma, C., Tran, V., Liang, Y., Walker, D.I., & Jones, D.P. (2020). Reference standardization for quantification and harmonization of large-scale metabolomics. Analytical Chem, 92(13), 8836-8844.