Dr. Kahe's research is primarily in nutritional and environmental epidemiology, focusing on lifestyle, dietary and environmental factors in relation to the risk of chronic diseases. He has served as the Principal Investigator in multiple NIH funded population studies, including secondary data analysis and studies collecting new data with multidisciplinary approach. Under the umbrella of CARDIA and REGARDS cohort studies, he has led a few NIH funded projects relating minerals (both nutritious and toxic) to cardiovascular disease, diabetes, and cognitive decline. As a co-investigator, he has been involved in a number of large national and international, epidemiological and clinical studies. In these studies, he has successfully administered and/or collaborated with other researchers from different institutes, and produced high quality peer-reviewed publications.
Areas of Expertise
Aging and Elderly, Child Health and Development, Cardiovascular Disease, Diabetes, Neurodevelopmental Disorders, Neurological Disease / Disorders, Stroke , Environmental Epidemiology, Toxicity of Heavy Metals, Nutrition, Obesity, Maternal Health, Perinatal Epidemiology
Lu L, Zhang Y, Chen C, Field RW, and Kahe K. Radon exposure and risk of cerebrovascular disease: a systematic review and meta-analysis in occupational and general population studies. Environmental Science and Pollution Research. 2022 Apr 23. doi: 10.1007/s11356-022-20241-x. Online ahead of print. PMID: 35460001.
Zhang Y, Lu L, Chen C, Field RW, D'Alton M, and Kahe K: Does protracted radon exposure play a role in the development of dementia? Environmental Research. 2022 Feb 18: 112980. doi: 10.1016/j.envres.2022.112980. Epub ahead of print. PMID: 35189101.
Chen C, Whitsel EA, Espeland MA, Snetselaar L, Hayden KM, Lamichhane AP, Serre ML, Vizuete W, Kaufman JD, Wang X, Chui HC, D'Alton ME, Chen JC, and Kahe K: B vitamin intakes modify the association between particulate air pollutants and incidence of all-cause dementia: findings from the Women's Health Initiative Memory Study. Alzheimer's & Dementia: The Journal of the Alzheimer's Association. 2022 Feb 1. doi: 10.1002/alz.12515. Online ahead of print. PMID: 35103387.
Chen C, Hayden KM, Kaufman J, Espeland MA, Whitsel EA, Serre ML, Vizuete W, Orchard TS, Wang X, Chui HC, D'Alton ME, Chen JC, and Kahe K: Adherence to a MIND-like dietary pattern, long-term exposure to fine particulate matter air pollution, and MRI-based measures of brain volume: The Women's Health Initiative Memory Study-MRI. Environmental Health Perspectives. 2021 Dec; 129 (12): 127008. doi: 10.1289/EHP8036. Epub 2021 Dec 23. PMID: 34939828.
Yang K, Chen C, Yan Q, Shen X, Jiang L, Ma R, Lu L, Zhu J, Tian Y, Cai W, D'Alton ME, Zhang J, Kahe K: Combined association of early exposure to long-chain n-3 polyunsaturated fatty acids, mercury and selenium with cognitive performance in 1-year-old infants. Environmental Research. 207: 112186, 2022. doi: 10.1016/j.envres.2021.112186. PMID: 34627802.
Lu L, Chen C, Li Y, Guo W, Zhang S, Brockman J, Shikany J, and Kahe K: Magnesium intake is inversely associated with risk of non-alcoholic fatty liver disease among American adults. European Journal of Nutrition. 61 (3): 1245 – 1254, 2022. doi: 10.1007/s00394-021-02732-8. PMID: 34741649.
Zhang Y, Shea MK, Judd S, D'Alton M, and Kahe K: Issues related to the research on vitamin K supplementation and bone mineral density. European Journal of Clinical Nutrition. 76 (3): 335 – 339, 2022. doi: 10.1038/s41430-021-00941-2. PMID: 34050327.
Li Y, Chen C, Lu L, Guo W, VanWagner LB, Shikany JM, Zhang S, and Kahe K: Cadmium exposure in young adulthood is associated with risk of nonalcoholic fatty liver disease in midlife. Digestive Diseases and Sciences. 67 (2): 689 – 696, 2022. doi: 10.1007/s10620-021-06869-8. PMID: 33630217.
Mattern L, Chen C, McClure LA, Brockman J, Cushman M, Judd S, and Kahe K: Serum zinc levels and incidence of ischemic stroke: The REasons for Geographic and Racial Differences in Stroke Study. Stroke. 52 (12): 3953 – 3960, 2021. doi:10.1161/STROKEAHA.120.033187. PMID: 34412513.
Ma R, Yang K, Chen C, Mao X, Shen X, Jiang L, Ouyang F, Tian Y, Zhang J, and Kahe K: Early-life exposure to aluminum and fine motor performance in infants: a longitudinal study. Journal of Exposure Science and Environmental Epidemiology. 31 (2): 248 – 256, 2021. doi: 10.1038/s41370-021-00294-9. PMID: 33597723.