Iuliana Ionita-Laza

Iuliana Ionita-Laza

Iuliana Ionita-Laza

Associate Professor


722 West 168th Street, Rm 646
New York NY USA 10032
Website address: Email:


Iuliana Ionita-Laza, PhD, focuses her research in the area of statistical genetics and, in particular, the development of statistical and computational methods for problems arising in human genetics. She is currently working on the optimal design of genetic variation discovery studies using the new sequencing technologies, methods for the analysis of copy-number variation data, methods to test for the effect of rare variants in complex traits, and two-stage designs in genome-wide association studies. On the applied side, Dr. Ionita-Laza is actively involved in a study investigating the effect of copy-number variants in childhood asthma as well as genetic studies on bipolar disorder and lung cancer.



PhD, 2006, New York University

Editorial Boards

Review Editorial Board, Frontiers in Statistical Genetics and Methodology

Honors & Awards

Janet Fabri Prize, Courant Institute of Mathematical Sciences, 2007
Dean's Dissertation Fellowship, New York University, 2005-2006
Second Prize, National Mathematical Competition, Romania 1996

Areas of Expertise

Neurological Disease / Disorders, Genetic Susceptibility, Genetics, Global Health

Select Publications

I Ionita-Laza, NM Laird On the optimal design of genetic variant discovery studies Statistical Applications in Genetics and Molecular Biology 2010
I Ionita-Laza, J Buxbaum, N Laird and C Lange A new testing strategy to identify rare variants with either risk or protective effect on disease PloS Genetics 2011
Iuliana Ionita-Laza, Christoph Lange, Nan Laird On a method to count the number of unseen variants in the human genome Proc Natl Acad Sci 106 5008-5013 2009
David Fardo, Iuliana Ionita-Laza, Christoph Lange On quality control measures in genome-wide association studies: A test to assess the genotyping quality of individual probands in family-based association studies and an application to the HapMap data Plos Genetics 2009
Lars Bertram, Christoph Lange et al., Iuliana Ionita-Laza, et al. R Tanzi Genome-wide Association Analysis Reveals Putative Alzheimer's Disease Susceptibility Loci in Addition to APOE American Journal of Human Genetics 83 623-632 2008
Jinbo Fan*, Iuliana Ionita-Laza*, et al., Nan Laird, Jordan Smoller Linkage Disequilibrium Mapping of the Chromosome 6q21-22.31 Bipolar I Disorder Susceptibility Locus Neuropsychiatric Genetics 2009
Iuliana Ionita-Laza, Nan Laird, Benjamin Raby, Scott Weiss, Christoph Lange On the frequency of copy number variants Bioinformatics 24 2350-2355 2008
Iuliana Ionita-Laza, Angela Rogers, Christoph Lange, Benjamin Raby, Charles Lee Genetic association analysis of copy number variation in human disease pathogenesis Genomics 93 22-26 2009
Iuliana Ionita-Laza, George Perry, Benjamin Raby, Barbara Klanderman, Charles Lee, Nan Laird, Scott Weiss, Christoph Lange On the analysis of copy-number variations in genome-wide association studies: A translation of the family-based association test Genetic Epidemiology 32 273-284 2008
Iuliana Ionita-Laza, Matthew McQueen, Nan Laird, Christoph Lange Genomewide Weighted Hypothesis Testing in Family-Based Association Studies, with an Application to a 100K Scan American Journal of Human Genetics 81 607-614 2007
Iuliana Ionita, Raul-Sam Daruwala, Bud Mishra Mapping Tumor Suppressor Genes using Multipoint Statistics from Copy-Number Variation Data American Journal of Human Genetics 79 13-22 2006
Iuliana Ionita, Shaw-Hwa Lo Multilocus Linkage Analysis of Affected Sib Pairs Human Heredity 60 227-240 2005

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