Robert N. Butler Columbia Aging Center

Publications

Selected Publications

Diagram of the components of intrinsic capacity

1. Beard JR, Si Y, Liu Z, Chenoweth L, Hanewald K. Intrinsic Capacity: Validation of a New WHO Concept for Healthy Aging in a Longitudinal Chinese Study. J Gerontol A Biol Sci Med Sci. 2022 Jan 7;77(1):94-100. doi: 10.1093/gerona/glab226.

 

 

 

Correlation of various metrics of aging

2. Belsky DW, Caspi A, Corcoran DL, Sugden K, Poulton R, Arseneault L, Baccarelli A, Chamarti K, Gao X, Hannon E, Harrington HL, Houts R, Kothari M, Kwon D, Mill J, Schwartz J, Vokonas P, Wang C, Williams BS, Moffitt TE. DunedinPACE, a DNA methylation biomarker of the pace of aging. Elife. 2022 Jan 14;11:e73420. doi: 10.7554/eLife.73420.

 

 

Coefficients of variation versus time before death

3. Cohen AA, Leung DL, Legault V, Gravel D, Blanchet FG, Côté AM, Fülöp T, Lee J, Dufour F, Liu M, Nakazato Y. Synchrony of biomarker variability indicates a critical transition: Application to mortality prediction in hemodialysis. iScience. 2022 May 10;25(6):104385. doi: 10.1016/j.isci.2022.104385.

 

 

Predicted rLTL versus Age

4. Cowell W, Tang D, Yu J, Guo J, Wang S, Baccarelli A, Perera F, Herbstman J. Telomere dynamics across the early life course: Findings from a longitudinal study in children. Psychoneuroendocrinology. 2021;129:105270. doi:10.1016/j.psyneuen.2021.105270

 

5. Fried LP, Cohen AA, Xue QL, Walston J, Bandeen-Roche K, Varadhan R. The physical frailty syndrome as a transition from homeostatic symphony to cacophony. Nature Aging. 2021 1(1):36-46. doi:10.1038/s43587-020-00017-z 

 

All odds ratios were less than 1

6. Makarem N, Castro-Diehl C, St-Onge MP, Redline S, Shea S, Lloyd-Jones D, Ning H, Aggarwal B. Redefining Cardiovascular Health to Include Sleep: Prospective Associations With Cardiovascular Disease in the MESA Sleep Study. J Am Heart Assoc. 2022 Nov;11(21):e025252. doi: 10.1161/JAHA.122.025252.

 

Bioenergetics and Health-Centered Model of Care

7. Picard M. Why Do We Care More About Disease than Health? Phenomics. 2022 Jan 28;2(3):145-155. doi: 10.1007/s43657-021-00037-8.

 

 

Associations with Lead SNPs

8. Verma A, Huffman JE, Rodriguez A, Conery M, Liu M, et al. Diversity and Scale: Genetic Architecture of 2,068 Traits in the VA Million Veteran Program. medRxiv [Preprint]. 2023 Jun 29:2023.06.28.23291975. doi: 10.1101/2023.06.28.23291975. 

 

9. Wang, T., Ionita-Laza, I. and Wei, Y.  Integrated Quantile RAnk Test (iQRAT) for gene-level associations in sequencing studies. Annals of Applied Statistics. 2022 Vol. 16(3), 1423-1444. doi: 10.1214/21-AOAS1548.