NEXUS (Network for Exposomics in the United States)

The U.S. National Institutes of Health (NIH) has selected Columbia University to oversee NEXUS: Network for Exposomics in the U.S. NEXUS is a coordinating Center and a movement to how our environments, or the exposome, shape human health, with the goal to transform the entire biomedical enterprise. By operationalizing exposomics, we’re integrating environmental data into all types of research, and achieving the genomics scale to identify the balance between genetic and environmental influences on health.

NEXUS is working to establish a framework and best practices for exposomics analysis of biological and environmental samples, develop a framework for geospatial-based exposomics studies of environmental and social influences on health and disease, and create a comprehensive exposomics digital framework to support precision environmental health.

NEXUS engages with multidisciplinary academic, community, and industry partners, in the U.S. and around the world, and will support bootcamps, conferences, and other learning opportunities to grow exposomics as a field, with attention to overcoming socioeconomic inequities.

The NEXUS Coordinating Center is led by Gary Miller, PhD, Vice Dean for Research Strategy and Innovation and Professor of Environmental Health Sciences, at Columbia University Mailman School of Public Health; Chirag Patel, PhD, Associate Professor of Biomedical Informatics at Harvard Medical School; and Rima Habre, ScD, Associate Professor of Population and Health Sciences at the University of Southern California.

Learn more on the NEXUS website:  https://www.nexus-exposomics.org/

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Collaborative Hubs

1. Administrative and Stakeholder Engagement Hub (Multiple PIs)

Building collaborative networks to fulfill the multi-disciplinary needs for inclusive exposome research.

Coordinating Center

2. ChemBio Analytical Sciences Hub

Disseminating and validating high-throughput exposure measurement technologies.

Hub Leads

3. Geospatial Sciences Hub

State-of-the art approaches to link place and time to exposure and health.

Hub Leads

4. NEXUS Data Sciences Hub

Developing digital infrastructure to support a new era of precision environmental health

Hub Leads

5. Collaborative Hub

Hub Leads

Funding Sources

We are proud to have funding support from the following NIH institutes and Office:

  • National Institute of Environmental Health Sciences (NIEHS)
  • National Institute on Aging (NIA)
  • National Institute of Neurological Disorders and Stroke (NINDS)
  • National Cancer Institute (NCI)
  • National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
  • Office of Research on Women’s Health (ORWH)

More information can be found on NIH RePORTER.