Overview
Academic Appointments
- Adjunct Assistant Professor of Epidemiology
Administrative Titles
- Member, Herbert Irving Comprehensive Cancer Center
Credentials & Experience
Education & Training
- BS, 1999 University of Connecticut
- MS, 2001 University of Connecticut
- ScD, 2007 Harvard University
Committees, Societies, Councils
http://www.epiresearch.org/'>Member, Society for Epidemiologic Research
http://www.nutrition.org/'>Member, American Society for Nutrition
Honors & Awards
Pilot Award, NIEHS Center for Environmental Health in Northern Manhattan, 2013
Calderone Prize for Junior Faculty Development, 2011
Research
Global Health Activities
Nutrients Involved in One-carbon Metabolism and the Methylation of Arsenic and DNA, Bangladesh: Chronic exposure to arsenic via contaminated drinking water is a worldwide problem associated with multiple adverse health effects. Metabolism of inorganic arsenic, which facilitates urinary excretion, relies on nutrient-dependent one-carbon metabolism and involves two methylation steps. Methylation of DNA is an epigenetic modification that plays important roles in the regulation of gene expression and may play a role in the underlying mechanism of arsenic-induced carcinogenesis. The overall purpose of this research is to investigate how several nutrients involved in one-carbon metabolism interact to influence arsenic and genomic DNA methylation.
B Vitamin Deficiencies, Arsenic, and Cognitive Function in Bangladeshi Adolescents, Bangladesh: The overall goal of this study is to test the hypothesis that suboptimal status of two nutrients, vitamin B12 and folate, and/or high plasma total homocysteine concentrations, either independently or in combination with arsenic exposure, are associated with impairments in cognitive function in 15-17 year-old Bangladeshi adolescents.